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J Bronchology Interv Pulmonol
Chest
Thorax
AJRCCM
Respirology
Lancet Respiratory Medicine
ERJ
Annals of ATS
J Bronchology Interv Pulmonol
Chest
Thorax
AJRCCM
Respirology
Lancet Respiratory Medicine
ERJ
Annals of ATS
◆ Editor's Selection

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BMC pulmonary medicine ⭐ Featured

Derivation and validation of a clinical prediction model incorporating the pleural fluid ADA-to-LDH ratio for differentiating tuberculous from malignant pleural effusions: a multi-center study.

Editor's Takeaway
A validated, multicenter nomogram integrating the pleural fluid ADA-to-LDH ratio offers a superior, user-friendly tool for distinguishing tuberculous from malignant pleural effusions. This predictive model enhances diagnostic accuracy by improving upon individual biomarker performance.
Pan Z; Tao S; Sheng H; Xu X; Lin Z; Huang F Review →

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Editorial Last Updated: May 9, 2026

Recent advancements in interventional pulmonology emphasize the integration of high-fidelity imaging, AI-driven navigation, and refined diagnostic biomarkers to optimize procedural safety and diagnostic yield. These data highlight a shift toward precision-based airway management and the mitigation of procedure-related infectious risks.

Optimizing Airway Imaging and Procedural Support

Dynamic CT imaging provides a definitive diagnostic framework for central airway obstruction, enabling clinicians to distinguish between tracheobronchomalacia (TBM) and excessive dynamic airway collapse (EDAC) based on specific cartilaginous versus membranous collapse patterns, as detailed in Distinguishing Tracheobronchomalacia and Excessive Dynamic Airway Collapse on Dynamic CT Images. Concurrently, High-Flow Nasal Cannula Versus Conventional Oxygen Therapy During Bronchoscopy: A Meta-Analysis of Randomized Controlled Trials confirms the utility of HFNC in maintaining oxygenation during bronchoscopic procedures, while the AIBAN-AI Bronchial Detection and Airway Navigation System introduces a YOLOv8-based architecture to improve real-time navigational precision.

Editor's Top Pick: Derivation and validation of a clinical prediction model incorporating the pleural fluid ADA-to-LDH ratio for differentiating tuberculous from malignant pleural effusions: a multi-center study. This nomogram represents a significant clinical advancement, providing a validated, high-accuracy diagnostic tool that outperforms individual biomarker analysis in the critical differentiation of pleural disease etiologies.

Safety, Risk Mitigation, and Diagnostic Precision

Procedural safety remains a priority, with Safety of flexible bronchoscopy in elderly patients demonstrating that age is not an independent predictor of adverse events, shifting the focus of risk assessment to procedural complexity. Conversely, Pulmonary infectious complications associated with the addition of cryobiopsy to conventional sampling for peripheral pulmonary lesions: a retrospective study identifies a 3.0% absolute increase in post-procedural infection risk (OR 2.84) associated with cryobiopsy, necessitating careful patient selection. Finally, Network-Based Analysis of Images and Lesions Expressed by Digital Interpretation and Transmission of Bronchoscopy Findings on Social Media (NAILED-IT) underscores the evolving role of digital platforms in bronchoscopic data dissemination.

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