Literature Archives

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Thorax

Comparative performance of endobronchial ultrasound-guided sampling techniques in patients with mediastinal lesions: a network meta-analysis.

Study Takeaway
While EBUS-TMC (RR 1.27, 95% CI 1.16 to 1.39) and EBUS-IFB may improve diagnostic yield over standard EBUS-TBNA—particularly in benign disease, sarcoidosis, and lymphoma—wide predictive intervals crossing unity mean these findings are hypothesis-generating and warrant caution in routine IP practice.
BMC pulmonary medicine

Conservative management of prolonged air leak following tension pneumothorax in cavitary pulmonary tuberculosis: a case report.

Study Takeaway
In clinically stable patients with adequate drainage and close supervision, a prolonged air leak in active cavitary tuberculosis can be managed conservatively rather than by duration alone, with the air leak ultimately resolving 61 days after hospital discharge.
Annals of the American Thoracic Society

Robotic Assisted Bronchoscopy with Endobronchial Ultrasound for the Evaluation of Multiple Pulmonary Nodules: A Multi-Center Registry.

Study Takeaway
Simultaneous sampling of multiple pulmonary nodules during one anesthesia event is feasible and safe, achieving a strict per-nodule diagnostic yield of 71.5% while providing adequate cellularity for next-generation sequencing in 82.6% of non-small cell lung cancer nodules.
The European respiratory journal

ERS Statement on ultrasound guided interventions in respiratory disease.

Study Takeaway
The use of ultrasound to guide percutaneous thoracic procedures shows higher success and lower complication rates in the reviewed evidence, helping to improve safety, effectiveness, and reduce healthcare costs.
BMC pulmonary medicine

Hemodynamic improvement but worsening hypoxemia after balloon pulmonary angioplasty: severe eosinophilic asthma unmasked in CTEPH.

Study Takeaway
Clinicians should consider competing ventilatory limitations such as severe eosinophilic asthma when hypoxemia worsens despite successful hemodynamic improvement following balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension patients.
BMC pulmonary medicine

Should we abandon the simple aspiration in favour of chest tube drainage in the management of spontaneous pneumothorax? A systematic review and meta-analysis.

Study Takeaway
Simple aspiration should remain prioritized over chest tube drainage in clinical management, as it showed a significantly lower adverse effect occurrence (OR = 0.22, 95% CI 0.08 to 0.61, p = 0.004) and shorter hospitalization without a difference in immediate success.
Annals of the American Thoracic Society

Thirty-Day Readmissions and Predictors of Adverse Outcomes After Bronchoscopic Lung Volume Reduction in the United States, 2019-2022.

Study Takeaway
Nearly one in ten patients undergoing bronchoscopic lung volume reduction are readmitted within thirty days, predominantly for respiratory issues like pneumothorax and COPD exacerbation. Clinicians should implement structured peri-discharge pathways targeting patients with index pneumothorax, which independently predicted readmission (OR 1.69, 95% CI 1.12-2.56), and those with a length of stay of six days or more.
BMC pulmonary medicine

Diagnostic yield and feasibility of EBUS-guided cautery-assisted transbronchial forceps biopsy for suspected benign mediastinal and hilar lymphadenopathy: a prospective self-controlled pilot study.

Study Takeaway
Adding cautery-assisted transbronchial forceps biopsy significantly improved patient-level diagnostic yield compared to standard EBUS-TBNA alone (85.7% vs. 21.4%, P < 0.001) without severe complications, though larger multicenter studies are still needed to confirm these findings.
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