Literature Archives

The age-adjusted mortality rate more than doubled from 0.79 in 1999 to 1.96 per 100,000 population in 2020, with an overall average annual percent change of + 4.71% (95% CI: 3.06-6.38), highlighting an urgent need for integrated pulmonary-renal care in clinical practice.

For interventional pulmonologists, this demonstrates that transbronchial cryobiopsy preserves delicate tumor immune microarchitecture without crush artifacts, overcoming traditional forceps biopsy limitations and enabling the assessment of tertiary lymphoid structure maturity for pretreatment immunotherapy profiling.

While endobronchial valves offered a safer, less invasive perioperative profile, surgical operation provided superior long-term recurrence-free survival (2-year rate: 86.5% vs. 70.0%; HR for EBV: 2.48, P < 0.001), particularly in patients with giant bullae of ≥ 10 cm.

Demonstrates a novel application of robotic platforms for targeted drainage of complex lung infections.

This study investigated airway surface liquid (ASL) pH and its regulating genes in healthy individuals and asthma patients to support the development of therapies that treat airway diseases by modifying lung acidity.

For interventional pulmonologists, these findings show that novel genomic classifiers can identify usual interstitial pneumonia patterns with 92% specificity, signaling a shift toward safer, precision-based diagnosis in clinical practice.

Consumer wearable devices effectively track real-time functional recovery by monitoring objective metrics such as step count and heart rate following interventions for malignant pleural effusion.

Combining the procedures demonstrated non-inferior 12-week pleurodesis success (89.5% versus 68.4%) while significantly reducing median hospital length of stay (1 versus 4 days, P < 0.001) and improving dyspnea scores.

Excessive dynamic airway collapse affects a significant portion of symptomatic chronic obstructive pulmonary disease patients and is independently predicted by body mass index, modified Medical Research Council, and COPD Assessment Test scores, with dynamic chest computed tomography achieving 93.1% sensitivity (95% CI 77.2-99.2) and 100% specificity (95% CI 92.3-100.0) for diagnosis.

For interventional pulmonologists, the serum LDH to ADA ratio emerged as a powerful discriminatory marker with an AUC of 0.938, sensitivity of 89.5%, and specificity of 91.3%, offering a reliable, minimally invasive way to guide clinical decisions when invasive procedures are limited.

Robotic bronchoscopy using C-arm-based tomosynthesis significantly increased median total radiation exposure per case to 0.237 mSv compared to conventional and standard fluoroscopy robotic methods (P = 0.025), meaning clinicians must carefully monitor imaging use to align with safety recommendations.

While overall diagnostic yield was similar across modalities, TBCB provided significantly higher-quality tissue for molecular profiling assays (P = 0.002) and less crush artifact compared to TBFB (P < 0.0001). Clinicians should consider supplementing EBUS-TBNA with TBFB or TBCB when suspecting inflammatory or lymphoproliferative conditions, or when high-quality tissue is needed for molecular assays.