Literature Archives

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Chest

Thoracentesis with pleural fluid cytology versus thoracoscopy with pleural biopsy for the diagnosis of malignant pleural effusion: a cost-effectiveness study.

Study Takeaway
Thoracentesis is the more cost-effective initial approach for cancers with pleural fluid cytology sensitivity greater than 27 percent, whereas medical thoracoscopy becomes more cost-effective for recurrent effusions following a negative thoracentesis.
American journal of respiratory and critical care medicine

Utilizing X-ray Velocimetry for Non-Invasive Evaluation of Collateral Ventilation in Bronchoscopic Lung Volume Reduction Procedures.

Study Takeaway
For interventional pulmonologists, X-ray Velocimetry shows strong discriminative ability for pre-procedural collateral ventilation risk stratification with an AUC of 0.862 (P = 0.002), though it cannot yet replace intraoperative Chartis testing due to modest sensitivity.
Respirology

Safety and Efficacy of Direct Cryobiopsy Specimen Retrieval Through the 3.0‐mm Working Channel of a Therapeutic Bronchoscope Using a 1.1‐mm Cryoprobe: A Multicentre Prospective Observational Study

Study Takeaway
Transbronchial cryobiopsy using a 1.1-mm probe through a therapeutic bronchoscope is safe and feasible, achieving an 87.5% overall diagnostic yield with significantly larger tissue samples than forceps biopsy and a 95.8% multiplex genetic testing success rate.
Thorax

Time to next procedure in patients with malignant pleural effusion undergoing aspiration: derivation and initial validation of the RED score.

Study Takeaway
Clinicians can now use the newly derived RED score—incorporating baseline respiratory rate, ultrasound effusion depth, and dyspnoea—to predict time to the next procedure, yielding areas under the receiver operator curve of 0.73 and 0.75 in the derivation cohort.
Respiratory medicine

VITAL Study: Real-World Comparison of Robotic and Imaging-Guided Bronchoscopy : Impact of Real-Time Imaging and Tool-Lesion Alignment on Diagnostic Yield.

Study Takeaway
Galaxy robotic bronchoscopy achieved a higher strict diagnostic yield than LungVision (87.6% versus 74.7%; OR 2.40, 95% CI 1.10-5.24; P = 0.03), though success was primarily driven by real-time imaging and tool-lesion alignment rather than platform type or breath-hold utilization.
Respirology

Role of Lung Marking in the Age of Sublobar Resection

Study Takeaway
Highlights the critical collaboration between interventional pulmonologists and thoracic surgeons for precise localization of small nodules prior to sublobar resection.
Journal of bronchology & interventional pulmonology

Development of a Tool to Assess Competency in Bronchoscopic Lung Volume Reduction Via Endobronchial Valve Placement.

Study Takeaway
The VSTAT instruments provide a reliable and objective method for assessing BLVR competency, demonstrating significant score increases across experience tiers (P < 0.001) that should be integrated into training and credentialing pathways.
Journal of bronchology & interventional pulmonology

Hemodynamic Effects of Topical Oxymetazoline During Pediatric Flexible Bronchoscopy.

Study Takeaway
Endobronchial oxymetazoline is associated with a mild increase in blood pressure and a decrease in heart rate, including a statistically significant increase in bradycardia (OR 1.92, 95% CI 1.09 to 3.40, P = 0.024), but it appears safe and well-tolerated without increasing the need for rescue medications.
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