Transbronchial lung cryobiopsy in fibrotic hypersensitivity pneumonitis: prognostic differences and intra-lobar variability.
Study Takeaway
Patients diagnosed via cryobiopsy showed significantly better overall survival than those diagnosed via surgical lung biopsy (HR 0.436, 95% CI 0.197 to 0.963, P = 0.035), likely due to insufficient subpleural sampling. Therefore, cryobiopsy should be used as a complementary tool to surgical biopsy, and its limitations must be carefully addressed during multidisciplinary discussions.