Literature Archives

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Respiratory research

Ultrasonic elastography-guided pleural biopsy followed by as-needed semi-rigid thoracoscopic pleural biopsy versus immediate semi-rigid thoracoscopic pleural biopsy for the diagnosis of pleural effusion (UPDATE-3): a protocol of randomised controlled trial.

Study Takeaway
This trial will determine if starting with ultrasound elastography-guided biopsy is non-inferior to semi-rigid thoracoscopy using a non-inferiority margin of - 5% for diagnostic yield, potentially shifting practice toward a less invasive step-up approach and reducing the need for thoracoscopy.
Respirology

Diagnostic Yield of EBUS Mediastinal Cryobiopsy Versus TBNA in Suspected Lymphoproliferative Disorders: A Prospective Multicentre Study

Study Takeaway
Endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy significantly outperforms standard transbronchial needle aspiration in diagnostic yield and overall accuracy for suspected mediastinal lymphoproliferative disorders.
BMC pulmonary medicine

Comparison of nasal and oral linear endobronchial ultrasound: a retrospective single-center study.

Study Takeaway
For interventional pulmonologists, the nasal approach is a safe and feasible alternative that offers practical advantages, including reduced sedative requirements and fewer hypoxemia-related interruptions, while maintaining comparable diagnostic performance and complication rates to the oral route.
BMC pulmonary medicine

Diagnostic value of EBUS-TBNA for intrathoracic tuberculous lymphadenitis: a retrospective cohort analysis stratified by anti-tuberculosis treatment duration.

Study Takeaway
EBUS-TBNA is a safe and highly effective diagnostic tool for tuberculous lymphadenitis, achieving an overall diagnostic sensitivity of 96.2% that remains consistent regardless of prior anti-tuberculosis treatment duration (P = 0.42).
Respiratory medicine

Challenging Uniform Size Criteria for EBUS-TBNA Sampling: Comparative Analysis by Lymph Node Station.

Study Takeaway
Because benign nodes showed significant size variation across stations (P < 0.001), particularly between stations 4R or 4L versus 7, clinicians should recognize that uniform size cutoffs for EBUS-TBNA may not be optimal across mediastinal stations.
BMC pulmonary medicine

Etiology-based management spectrum and outcomes of pediatric central airway stenosis: a retrospective cohort study.

Study Takeaway
For interventional pulmonologists, treatment strategies significantly correlate with etiology, with acquired stenosis primarily managed by flexible bronchoscopic intervention at 94.1 percent and all groups exhibiting high overall efficacy rates between 80.4 percent and 94.1 percent.
Respiratory medicine

Comparative Outcomes Based on Pre-Bronchoscopic Lung Volume Reduction (BLVR) Six-Minute Walk Distance (6MWD).

Study Takeaway
While pre-procedure 6-minute walk distance did not significantly affect FEV1 responder rates or St. George's Respiratory Questionnaire improvements at 12 months, patients in the low functional capacity group experienced the greatest average increase in 6-minute walk distance (53.3 meters), whereas the high functionality group actually showed a decrease (53.2 meters).
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